NMDA and HIV-1 coat protein, GP120, produce necrotic but not apoptotic cell death in human CHP100 neuroblastoma cultures via a mechanism involving calpain.

Corasaniti, M T

NMDA and HIV-1 coat protein, GP120, produce necrotic but not apoptotic cell death in human CHP100 neuroblastoma cultures via a mechanism involving calpain. [electronic resource] - Biochemical and biophysical research communications Dec 1996 - 299-304 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-291X

10.1006/bbrc.1996.1796 doi


Calcium--metabolism
Calpain--antagonists & inhibitors
Cell Death
Cell Nucleus--ultrastructure
Cysteine Proteinase Inhibitors--pharmacology
Enzyme Activation
HIV Envelope Protein gp120--toxicity
Humans
N-Methylaspartate--toxicity
Necrosis
Neuroblastoma
Neurons--drug effects
Neurotoxins--toxicity
Receptors, N-Methyl-D-Aspartate--metabolism
Tumor Cells, Cultured