Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2).

Oshima, M

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). [electronic resource] - Cell Nov 1996 - 803-9 p. digital

Publication Type: Journal Article

0092-8674

10.1016/s0092-8674(00)81988-1 doi


Adenomatous Polyposis Coli--drug therapy
Adenomatous Polyposis Coli Protein
Animals
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--pharmacology
Cytoskeletal Proteins--genetics
Disease Models, Animal
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Extracellular Space--physiology
Female
Furans--pharmacology
Gene Dosage
Gene Expression Regulation, Enzymologic--physiology
Gene Expression Regulation, Neoplastic--physiology
Genes, APC--physiology
Intestinal Mucosa--enzymology
Isoenzymes--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mutagenesis--physiology
Prostaglandin-Endoperoxide Synthases--drug effects
Sulindac--pharmacology
Time Factors