In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation.

Webster, E L

In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation. [electronic resource] - Endocrinology Dec 1996 - 5747-50 p. digital

Publication Type: Journal Article

0013-7227

10.1210/endo.137.12.8940412 doi


Adrenocorticotropic Hormone--antagonists & inhibitors
Animals
Binding, Competitive
Carrageenan--administration & dosage
Cerebellum--metabolism
Corticotropin-Releasing Hormone--metabolism
Frontal Lobe--metabolism
Inflammation--chemically induced
Injections, Subcutaneous
Male
Myocardium--metabolism
Pituitary Gland--metabolism
Pyrimidines--pharmacology
Pyrroles--pharmacology
Rats
Rats, Sprague-Dawley
Receptors, Corticotropin-Releasing Hormone--antagonists & inhibitors
Sheep