Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow.

Alkayed, N J

Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. [electronic resource] - The American journal of physiology Oct 1996 - H1541-6 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0002-9513

10.1152/ajpheart.1996.271.4.H1541 doi


Animals
Arachidonic Acid--antagonists & inhibitors
Astrocytes--metabolism
Brain--cytology
Cells, Cultured
Cerebrovascular Circulation--drug effects
Cytochrome P-450 CYP2J2
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System
Male
Miconazole--pharmacology
Microcirculation--drug effects
Nitric Oxide Synthase--metabolism
Oxygenases--antagonists & inhibitors
Rats
Rats, Sprague-Dawley