Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: rationalization of CYP1A substrate specificity in terms of active site amino acid residues.

Lewis, D F

Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: rationalization of CYP1A substrate specificity in terms of active site amino acid residues. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Jul 1996 - 723-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0049-8254

10.3109/00498259609046745 doi


Amino Acid Sequence
Animals
Binding Sites
Camphor 5-Monooxygenase--antagonists & inhibitors
Cytochrome P-450 CYP1A1--antagonists & inhibitors
Cytochrome P-450 CYP1A2--chemistry
Cytochrome P-450 CYP1A2 Inhibitors
Enzyme Inhibitors--metabolism
Humans
Mice
Models, Molecular
Molecular Sequence Data
Molecular Structure
Rabbits
Rats
Sequence Alignment
Substrate Specificity
Trout