Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis.

Hefner, J

Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis. [electronic resource] - Chemistry & biology Jun 1996 - 479-89 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

1074-5521

10.1016/s1074-5521(96)90096-4 doi


Alkenes--chemistry
Catalysis
Cells, Cultured
Cytochrome P-450 Enzyme System--metabolism
Diterpenes--chemistry
Hydroxylation
Oxygen--metabolism
Paclitaxel--biosynthesis