Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation.
Ghosh, A K
Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation. [electronic resource] - Journal of medicinal chemistry Aug 1996 - 3278-90 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm960128k doi
Amino Acid Sequence
Aspartic Acid
Binding Sites
Crystallography, X-Ray
Drug Design
Furans--chemical synthesis
HIV Protease--chemistry
HIV Protease Inhibitors--chemical synthesis
HIV-1--enzymology
Hydrogen Bonding
Ligands
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Structure
Optical Rotation
Stereoisomerism
Structure-Activity Relationship
Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation. [electronic resource] - Journal of medicinal chemistry Aug 1996 - 3278-90 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm960128k doi
Amino Acid Sequence
Aspartic Acid
Binding Sites
Crystallography, X-Ray
Drug Design
Furans--chemical synthesis
HIV Protease--chemistry
HIV Protease Inhibitors--chemical synthesis
HIV-1--enzymology
Hydrogen Bonding
Ligands
Magnetic Resonance Spectroscopy
Models, Molecular
Molecular Structure
Optical Rotation
Stereoisomerism
Structure-Activity Relationship