Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

Bories, J C

Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1996 - 7871-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.93.15.7871 doi


Alleles
Animals
B-Lymphocytes--immunology
Base Sequence
Blastocyst
Cells, Cultured
Chimera
DNA Nucleotidyltransferases--metabolism
DNA Primers
DNA-Binding Proteins
Enhancer Elements, Genetic
Gene Deletion
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Genetic Complementation Test
Genomic Library
Immunoglobulin Heavy Chains--genetics
Immunoglobulin Joining Region--biosynthesis
Immunoglobulin Variable Region--biosynthesis
Mice
Molecular Sequence Data
Polymerase Chain Reaction
Proteins--genetics
Receptors, Antigen, T-Cell, alpha-beta--biosynthesis
Restriction Mapping
Sequence Deletion
Spleen--immunology
Stem Cells
Transcription, Genetic
VDJ Recombinases