Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex.

Poklar, N

Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1996 - 7606-11 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.93.15.7606 doi


Base Sequence
Calorimetry, Differential Scanning
Circular Dichroism
Cisplatin--pharmacology
Cross-Linking Reagents--pharmacology
DNA--chemistry
Deoxyguanosine--analogs & derivatives
Molecular Sequence Data
Nucleic Acid Conformation--drug effects
Nucleic Acid Denaturation
Oligodeoxyribonucleotides--chemical synthesis
Spectrophotometry, Ultraviolet
Structure-Activity Relationship
Thermodynamics