In vitro and in vivo pharmacology of S 16474, a novel dual tachykinin NK1 and NK2 receptor antagonist.

Robineau, P

In vitro and in vivo pharmacology of S 16474, a novel dual tachykinin NK1 and NK2 receptor antagonist. [electronic resource] - European journal of pharmacology Dec 1995 - 677-84 p. digital

Publication Type: Journal Article

0014-2999

10.1016/0014-2999(95)00604-4 doi


Animals
Bronchoconstriction--drug effects
Capillary Permeability--drug effects
Cell Degranulation--drug effects
Guinea Pigs
Humans
In Vitro Techniques
Male
Mast Cells--drug effects
Neurokinin-1 Receptor Antagonists
Oligopeptides--metabolism
Rabbits
Rats
Rats, Sprague-Dawley
Receptors, Neurokinin-1--metabolism
Receptors, Neurokinin-2--antagonists & inhibitors
Salivation--drug effects
Substance P--pharmacology