Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors.
van der Donk, W A
Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors. [electronic resource] - Biochemistry Jun 1996 - 8381-91 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi960190j doi
Alkylation
Animals
Antineoplastic Agents--pharmacology
Base Sequence
Deoxycytosine Nucleotides--pharmacology
Electron Spin Resonance Spectroscopy
Enzyme Inhibitors--pharmacology
Escherichia coli--enzymology
Isomerism
Kinetics
Mice
Models, Chemical
Molecular Sequence Data
Mutation
Pigments, Biological
Ribonucleotide Reductases--antagonists & inhibitors
Inactivation of ribonucleotide reductase by (E)-2'-fluoromethylene-2'-deoxycytidine 5'-diphosphate: a paradigm for nucleotide mechanism-based inhibitors. [electronic resource] - Biochemistry Jun 1996 - 8381-91 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi960190j doi
Alkylation
Animals
Antineoplastic Agents--pharmacology
Base Sequence
Deoxycytosine Nucleotides--pharmacology
Electron Spin Resonance Spectroscopy
Enzyme Inhibitors--pharmacology
Escherichia coli--enzymology
Isomerism
Kinetics
Mice
Models, Chemical
Molecular Sequence Data
Mutation
Pigments, Biological
Ribonucleotide Reductases--antagonists & inhibitors