Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis.

Boolbol, S K

Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. [electronic resource] - Cancer research Jun 1996 - 2556-60 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0008-5472


Adenomatous Polyposis Coli--drug therapy
Animals
Apoptosis
Base Sequence
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--therapeutic use
Cytokines--genetics
DNA Primers--chemistry
Epithelial Cells
Female
Gene Expression
Intestinal Mucosa--cytology
Isoenzymes--metabolism
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Molecular Sequence Data
Prostaglandin-Endoperoxide Synthases--metabolism
RNA, Messenger--genetics
Sulindac--therapeutic use