A single dose of granulocyte-macrophage colony-stimulating factor induces systemic interleukin-8 release and neutrophil activation in healthy volunteers.

van Pelt, L J

A single dose of granulocyte-macrophage colony-stimulating factor induces systemic interleukin-8 release and neutrophil activation in healthy volunteers. [electronic resource] - Blood Jun 1996 - 5305-13 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0006-4971


Adult
Cytoplasmic Granules--metabolism
Eosinophils--drug effects
Gene Expression Regulation--drug effects
Granulocyte-Macrophage Colony-Stimulating Factor--administration & dosage
Humans
Immunophenotyping
Injections, Subcutaneous
Interleukin-6--metabolism
Interleukin-8--metabolism
Kinetics
L-Selectin--biosynthesis
Lactoferrin--metabolism
Leukocyte Count--drug effects
Leukocyte Elastase
Macrophage-1 Antigen--biosynthesis
Male
Monocytes--drug effects
Neutrophils--drug effects
Pancreatic Elastase--metabolism
Receptors, IgG--biosynthesis
Recombinant Proteins--administration & dosage
Tumor Necrosis Factor-alpha--metabolism