DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complex.

Critchlow, S E

DNA cleavage is not required for the binding of quinolone drugs to the DNA gyrase-DNA complex. [electronic resource] - Biochemistry Jun 1996 - 7387-93 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-2960

10.1021/bi9603175 doi


Anti-Infective Agents--metabolism
Base Sequence
Binding Sites
Calcium--pharmacology
Ciprofloxacin--metabolism
Cloning, Molecular
DNA--metabolism
DNA Primers
DNA Topoisomerases, Type II--chemistry
DNA, Superhelical--metabolism
Kinetics
Macromolecular Substances
Molecular Sequence Data
Mutagenesis, Site-Directed
Point Mutation
Polymerase Chain Reaction
Recombinant Proteins--chemistry
Restriction Mapping
Transcription, Genetic
Tyrosine