Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain.

Stancato, L F

Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain. [electronic resource] - The Journal of biological chemistry Apr 1996 - 8831-6 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.271.15.8831 doi


Animals
Binding Sites
CHO Cells
Cricetinae
HSP90 Heat-Shock Proteins--chemistry
L Cells
Macromolecular Substances
Mice
Monoiodotyrosine--analogs & derivatives
Peptide Mapping
Protein Conformation
Receptors, Glucocorticoid--chemistry
Recombinant Proteins
Sulfhydryl Reagents--chemistry