Synthesis and antitumor evaluation of a highly potent cytotoxic DNA cross-linking polyamine analogue, 1,12-diaziridinyl-4,9-diazadodecane.
Li, Y
Synthesis and antitumor evaluation of a highly potent cytotoxic DNA cross-linking polyamine analogue, 1,12-diaziridinyl-4,9-diazadodecane. [electronic resource] - Journal of medicinal chemistry Jan 1996 - 339-41 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm9500885 doi
Animals
Antineoplastic Agents--administration & dosage
Aziridines--administration & dosage
Cross-Linking Reagents--chemical synthesis
DNA--drug effects
Electrophoresis, Agar Gel
Female
Leukemia L1210--drug therapy
Mechlorethamine--pharmacology
Melphalan--pharmacology
Mice
Mice, Inbred Strains
Spermine--administration & dosage
Thiotepa--pharmacology
Synthesis and antitumor evaluation of a highly potent cytotoxic DNA cross-linking polyamine analogue, 1,12-diaziridinyl-4,9-diazadodecane. [electronic resource] - Journal of medicinal chemistry Jan 1996 - 339-41 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm9500885 doi
Animals
Antineoplastic Agents--administration & dosage
Aziridines--administration & dosage
Cross-Linking Reagents--chemical synthesis
DNA--drug effects
Electrophoresis, Agar Gel
Female
Leukemia L1210--drug therapy
Mechlorethamine--pharmacology
Melphalan--pharmacology
Mice
Mice, Inbred Strains
Spermine--administration & dosage
Thiotepa--pharmacology