Design, synthesis, and structure-activity relationship studies of novel 1-[(1-acyl-4-piperidyl)methyl]-1H-2- methylimidazo[4,5-c]pyridine derivatives as potent, orally active platelet-activating factor antagonists.
Carceller, E
Design, synthesis, and structure-activity relationship studies of novel 1-[(1-acyl-4-piperidyl)methyl]-1H-2- methylimidazo[4,5-c]pyridine derivatives as potent, orally active platelet-activating factor antagonists. [electronic resource] - Journal of medicinal chemistry Jan 1996 - 487-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2623
10.1021/jm950555i doi
Animals
Dogs
Drug Design
Imidazoles--chemical synthesis
Magnetic Resonance Spectroscopy
Male
Mice
Platelet Activating Factor--antagonists & inhibitors
Platelet Aggregation Inhibitors--chemical synthesis
Pyridines--chemical synthesis
Rabbits
Rats
Rats, Sprague-Dawley
Structure-Activity Relationship
Design, synthesis, and structure-activity relationship studies of novel 1-[(1-acyl-4-piperidyl)methyl]-1H-2- methylimidazo[4,5-c]pyridine derivatives as potent, orally active platelet-activating factor antagonists. [electronic resource] - Journal of medicinal chemistry Jan 1996 - 487-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-2623
10.1021/jm950555i doi
Animals
Dogs
Drug Design
Imidazoles--chemical synthesis
Magnetic Resonance Spectroscopy
Male
Mice
Platelet Activating Factor--antagonists & inhibitors
Platelet Aggregation Inhibitors--chemical synthesis
Pyridines--chemical synthesis
Rabbits
Rats
Rats, Sprague-Dawley
Structure-Activity Relationship