Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.

Johnson, M R

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jun 1993 - 5539-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.90.12.5539 doi


Blotting, Northern
Blotting, Southern
DNA, Neoplasm--genetics
GTPase-Activating Proteins
Gene Expression
Gene Expression Regulation, Neoplastic
Genes, Neurofibromatosis 1
Genes, ras
Guanine Nucleotides--metabolism
Humans
In Situ Hybridization, Fluorescence
Kinetics
Melanoma
Neuroblastoma
Neurofibromin 1
Phosphates--metabolism
Protein Biosynthesis
Proteins--genetics
RNA, Messenger--isolation & purification
RNA, Neoplasm--genetics
Tumor Cells, Cultured
ras GTPase-Activating Proteins