Reduction of hepatic phosphoenolpyruvate carboxykinase (PEPCK) activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is due to decreased mRNA levels.

Stahl, B U

Reduction of hepatic phosphoenolpyruvate carboxykinase (PEPCK) activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is due to decreased mRNA levels. [electronic resource] - Toxicology Mar 1993 - 81-95 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0300-483X

10.1016/0300-483x(93)90207-9 doi


Animals
Cytochrome P-450 CYP1A1
Cytochrome P-450 Enzyme System--biosynthesis
Liver--enzymology
Male
Oxidoreductases--biosynthesis
Phosphoenolpyruvate Carboxykinase (GTP)--drug effects
Polychlorinated Dibenzodioxins--toxicity
RNA, Messenger--analysis
Rats
Rats, Sprague-Dawley
Receptors, Glucocorticoid--drug effects
Tryptophan Oxygenase--drug effects