Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axis.

Morgan, E T

Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axis. [electronic resource] - Biochemical pharmacology Jan 1993 - 415-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-2952

10.1016/0006-2952(93)90078-b doi


Acute-Phase Reaction--metabolism
Animals
Cytochrome P-450 Enzyme System--biosynthesis
Cytokines--pharmacology
Down-Regulation--drug effects
Female
Gene Expression Regulation--drug effects
Growth Hormone--administration & dosage
Haptoglobins--genetics
Hypophysectomy
Inflammation--metabolism
Isoenzymes--biosynthesis
Lipopolysaccharides--pharmacology
Liver--drug effects
Male
RNA, Messenger--analysis
Rats
Rats, Sprague-Dawley