32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis.

Frye, L L

32-Methyl-32-oxylanosterols: dual-action inhibitors of cholesterol biosynthesis. [electronic resource] - Journal of medicinal chemistry Feb 1993 - 410-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-2623

10.1021/jm00055a012 doi


Animals
CHO Cells
Cholesterol--biosynthesis
Cricetinae
Cytochrome P-450 Enzyme Inhibitors
Drug Design
Hydroxymethylglutaryl-CoA Reductase Inhibitors
In Vitro Techniques
Oxidoreductases--antagonists & inhibitors
Rats
Sterol 14-Demethylase
Sterols--chemical synthesis