Induction of RAR-beta 2 gene expression in embryos and RAR-beta 2 transactivation by the synthetic retinoid Ro 13-6307 correlates with its high teratogenic potency.
Soprano, D R
Induction of RAR-beta 2 gene expression in embryos and RAR-beta 2 transactivation by the synthetic retinoid Ro 13-6307 correlates with its high teratogenic potency. [electronic resource] - Toxicology and applied pharmacology Sep 1993 - 159-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0041-008X
10.1006/taap.1993.1183 doi
Animals
Carrier Proteins--genetics
Embryo, Mammalian--drug effects
Fatty Acids, Unsaturated--toxicity
Female
Gene Expression Regulation--drug effects
Mice
Pregnancy
RNA, Messenger--genetics
Receptors, Retinoic Acid
Stereoisomerism
Teratogens--toxicity
Transcription, Genetic--drug effects
Transcriptional Activation--drug effects
Tretinoin
Induction of RAR-beta 2 gene expression in embryos and RAR-beta 2 transactivation by the synthetic retinoid Ro 13-6307 correlates with its high teratogenic potency. [electronic resource] - Toxicology and applied pharmacology Sep 1993 - 159-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0041-008X
10.1006/taap.1993.1183 doi
Animals
Carrier Proteins--genetics
Embryo, Mammalian--drug effects
Fatty Acids, Unsaturated--toxicity
Female
Gene Expression Regulation--drug effects
Mice
Pregnancy
RNA, Messenger--genetics
Receptors, Retinoic Acid
Stereoisomerism
Teratogens--toxicity
Transcription, Genetic--drug effects
Transcriptional Activation--drug effects
Tretinoin