Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Baldwin, E T
Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1993 - 6796-800 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.90.14.6796 doi
Amino Acid Sequence
Aspartic Acid Endopeptidases--chemistry
Biological Transport
Cathepsin D--antagonists & inhibitors
Drug Design
Glycosylation
Humans
Lysosomes
Models, Molecular
Molecular Sequence Data
Pepstatins--chemistry
Phosphotransferases
Protein Conformation
Renin--chemistry
X-Ray Diffraction
Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jul 1993 - 6796-800 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.90.14.6796 doi
Amino Acid Sequence
Aspartic Acid Endopeptidases--chemistry
Biological Transport
Cathepsin D--antagonists & inhibitors
Drug Design
Glycosylation
Humans
Lysosomes
Models, Molecular
Molecular Sequence Data
Pepstatins--chemistry
Phosphotransferases
Protein Conformation
Renin--chemistry
X-Ray Diffraction