Determination and metabolism of dithiol chelating agents: the zinc chelate of the dimethyl ester of meso-2,3-dimercaptosuccinic acid increase biliary excretion of cadmium and platinum.
Aposhian, H V
Determination and metabolism of dithiol chelating agents: the zinc chelate of the dimethyl ester of meso-2,3-dimercaptosuccinic acid increase biliary excretion of cadmium and platinum. [electronic resource] - Chemical research in toxicology - 208-14 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0893-228X
10.1021/tx00032a010 doi
Animals
Bile--drug effects
Cadmium--metabolism
Cadmium Radioisotopes
Chelating Agents--chemistry
Cisplatin--toxicity
Edetic Acid--pharmacology
Kidney--drug effects
Kidney Diseases--chemically induced
Lethal Dose 50
Male
Mice
Platinum--metabolism
Quaternary Ammonium Compounds--metabolism
Rats
Rats, Sprague-Dawley
Succimer--chemistry
Zinc--pharmacology
Determination and metabolism of dithiol chelating agents: the zinc chelate of the dimethyl ester of meso-2,3-dimercaptosuccinic acid increase biliary excretion of cadmium and platinum. [electronic resource] - Chemical research in toxicology - 208-14 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0893-228X
10.1021/tx00032a010 doi
Animals
Bile--drug effects
Cadmium--metabolism
Cadmium Radioisotopes
Chelating Agents--chemistry
Cisplatin--toxicity
Edetic Acid--pharmacology
Kidney--drug effects
Kidney Diseases--chemically induced
Lethal Dose 50
Male
Mice
Platinum--metabolism
Quaternary Ammonium Compounds--metabolism
Rats
Rats, Sprague-Dawley
Succimer--chemistry
Zinc--pharmacology