Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.

Datta, R

Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 1993 - 2419-22 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.90.6.2419 doi


Actins--genetics
Animals
Base Sequence
Cell Nucleus--metabolism
Chickens
Chloramphenicol O-Acetyltransferase--biosynthesis
Clone Cells
DNA-Binding Proteins--genetics
Early Growth Response Protein 1
Gene Expression Regulation, Neoplastic--drug effects
Globins--genetics
Humans
Hydrogen Peroxide--pharmacology
Immediate-Early Proteins
Leukemia, Promyelocytic, Acute
Molecular Sequence Data
Oligodeoxyribonucleotides
Promoter Regions, Genetic
Recombinant Fusion Proteins--biosynthesis
Simplexvirus--genetics
Tetradecanoylphorbol Acetate--pharmacology
Thymidine Kinase--biosynthesis
Transcription Factors--genetics
Transcription, Genetic--radiation effects
Tumor Cells, Cultured
X-Rays