Human TNF mutants with selective activity on the p55 receptor.

Van Ostade, X

Human TNF mutants with selective activity on the p55 receptor. [electronic resource] - Nature Jan 1993 - 266-9 p. digital

Publication Type: Comparative Study; Journal Article

0028-0836

10.1038/361266a0 doi


Adenocarcinoma--drug therapy
Amino Acid Sequence
Animals
Binding, Competitive
Cell Survival--drug effects
Colonic Neoplasms--drug therapy
Cycloheximide--pharmacology
Female
Granulocyte-Macrophage Colony-Stimulating Factor--biosynthesis
Humans
Kinetics
L Cells
Mice
Mice, Nude
Neoplasm Transplantation
Point Mutation
Receptors, Cell Surface--drug effects
Receptors, Tumor Necrosis Factor
Recombinant Proteins--drug effects
Transfection
Transplantation, Heterologous
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha--genetics