Simvastatin inhibits the oxidation of low-density lipoproteins by activated human monocyte-derived macrophages.

Giroux, L M

Simvastatin inhibits the oxidation of low-density lipoproteins by activated human monocyte-derived macrophages. [electronic resource] - Biochimica et biophysica acta Jan 1993 - 335-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-3002

10.1016/0005-2760(93)90145-y doi


Drug Interactions
Humans
Hydroxymethylglutaryl CoA Reductases--pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoproteins, LDL--metabolism
Lovastatin--analogs & derivatives
Macrophage Activation
Macrophages--drug effects
Mevalonic Acid--pharmacology
Monocytes--drug effects
Oxidation-Reduction--drug effects
Simvastatin
Superoxides--metabolism
Tetradecanoylphorbol Acetate--pharmacology