Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Kaufmann, S H

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. [electronic resource] - Cancer research Sep 1993 - 3976-85 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0008-5472


Antineoplastic Agents--pharmacology
Apoptosis--physiology
Blotting, Western
Etoposide--pharmacology
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy
Leukemia, Myeloid, Acute--drug therapy
Leukemia, Promyelocytic, Acute--drug therapy
Molecular Weight
NAD--metabolism
Peptide Fragments--analysis
Poly(ADP-ribose) Polymerases--chemistry
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Protease Inhibitors--pharmacology