Development and functional characterization of a murine/human chimeric antibody with specificity for the human interleukin-2 receptor.

Vandevyver, C

Development and functional characterization of a murine/human chimeric antibody with specificity for the human interleukin-2 receptor. [electronic resource] - Molecular immunology Jul 1993 - 865-76 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0161-5890

10.1016/0161-5890(93)90010-9 doi


Amino Acid Sequence
Animals
Antibodies, Monoclonal--biosynthesis
Antibody Specificity
Antibody-Dependent Cell Cytotoxicity
Base Sequence
Binding, Competitive
Blotting, Western
Complement System Proteins--immunology
Dose-Response Relationship, Immunologic
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Humans
Hybridomas
Immunoglobulin Heavy Chains--chemistry
Immunoglobulin Light Chains--chemistry
Immunoglobulin Variable Region--chemistry
Lymphocyte Activation--immunology
Mice
Molecular Sequence Data
Receptors, Interleukin-2--immunology
Recombinant Fusion Proteins--biosynthesis
Transfection
Tumor Cells, Cultured