Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis.

Philips, A

Estradiol increases and anti-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis. [electronic resource] - The Journal of biological chemistry Jul 1993 - 14103-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258


Breast Neoplasms
Chloramphenicol O-Acetyltransferase--genetics
Epidermal Growth Factor--pharmacology
Estradiol--analogs & derivatives
Estrogen Antagonists--pharmacology
Female
Genes, fos--drug effects
Genes, jun--drug effects
Humans
Insulin-Like Growth Factor I--pharmacology
Kinetics
Polyunsaturated Alkamides
Proto-Oncogene Proteins c-fos--biosynthesis
Proto-Oncogene Proteins c-jun--biosynthesis
RNA, Messenger--biosynthesis
Receptors, Estrogen--drug effects
Recombinant Fusion Proteins--drug effects
Tamoxifen--analogs & derivatives
Thymidine Kinase--genetics
Time Factors
Transfection
Tumor Cells, Cultured