Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype.

Strittmatter, W J

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. [electronic resource] - Experimental neurology Feb 1994 - 163-71; discussion 172-4 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review

0014-4886

10.1006/exnr.1994.1019 doi


Alzheimer Disease--genetics
Amyloid beta-Peptides--genetics
Apolipoprotein E4
Apolipoproteins E--genetics
Chromosomes
Genetic Linkage
Humans
Microtubules--pathology
Neurofibrillary Tangles--pathology
Phosphorylation
tau Proteins--metabolism