Deamidation and isoaspartate formation during in vitro aging of recombinant tissue plasminogen activator.

Paranandi, M V

Deamidation and isoaspartate formation during in vitro aging of recombinant tissue plasminogen activator. [electronic resource] - The Journal of biological chemistry Jan 1994 - 243-53 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258


Alkylation
Amides--metabolism
Amino Acid Sequence
Animals
Aspartic Acid--metabolism
CHO Cells
Cricetinae
Disulfides--metabolism
Humans
Kinetics
Methylation
Molecular Sequence Data
Oxidation-Reduction
Peptide Mapping
Recombinant Proteins--metabolism
Tissue Plasminogen Activator--metabolism
Trypsin--metabolism