Human progelatinase A can be activated by autolysis at a rate that is concentration-dependent and enhanced by heparin bound to the C-terminal domain.

Crabbe, T

Human progelatinase A can be activated by autolysis at a rate that is concentration-dependent and enhanced by heparin bound to the C-terminal domain. [electronic resource] - European journal of biochemistry Dec 1993 - 431-8 p. digital

Publication Type: Journal Article

0014-2956

10.1111/j.1432-1033.1993.tb18393.x doi


Amino Acid Sequence
Binding Sites
Chromatography, Ion Exchange
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Enzyme Precursors--isolation & purification
Gelatinases--isolation & purification
Heparin--metabolism
Humans
Hydrolysis
Matrix Metalloproteinase 2
Metalloendopeptidases--isolation & purification
Molecular Sequence Data
Peptide Fragments--chemistry
Recombinant Proteins--isolation & purification
Sodium Chloride