Synthesis and reaction of potential alternate substrates and mechanism-based inhibitors of clavaminate synthase.

Iwata-Reuyl, D

Synthesis and reaction of potential alternate substrates and mechanism-based inhibitors of clavaminate synthase. [electronic resource] - Journal of natural products Aug 1993 - 1373-96 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0163-3864

10.1021/np50098a022 doi


Aza Compounds--chemistry
Clavulanic Acids--chemical synthesis
Cyclization
Hydroxylation
Indicators and Reagents
Mixed Function Oxygenases--antagonists & inhibitors
Molecular Conformation
Prodrugs--chemistry
Stereoisomerism
Structure-Activity Relationship
Substrate Specificity
Trimethylsilyl Compounds--chemistry