Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues.
Ashton, M J
Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. [electronic resource] - Journal of medicinal chemistry May 1994 - 1696-703 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm00037a021 doi
3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors
Animals
Aorta--enzymology
Asthma--drug therapy
Benzamides--chemical synthesis
Bronchial Spasm--chemically induced
Eosinophils--drug effects
Guinea Pigs
Histamine--pharmacology
Isoenzymes--antagonists & inhibitors
Kinetics
Male
Molecular Structure
Phosphodiesterase Inhibitors--chemical synthesis
Pyridines--chemical synthesis
Structure-Activity Relationship
Superoxides--metabolism
Swine
Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues. [electronic resource] - Journal of medicinal chemistry May 1994 - 1696-703 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm00037a021 doi
3',5'-Cyclic-AMP Phosphodiesterases--antagonists & inhibitors
Animals
Aorta--enzymology
Asthma--drug therapy
Benzamides--chemical synthesis
Bronchial Spasm--chemically induced
Eosinophils--drug effects
Guinea Pigs
Histamine--pharmacology
Isoenzymes--antagonists & inhibitors
Kinetics
Male
Molecular Structure
Phosphodiesterase Inhibitors--chemical synthesis
Pyridines--chemical synthesis
Structure-Activity Relationship
Superoxides--metabolism
Swine