Polyol pathway mediates high glucose-induced collagen synthesis in proximal tubule.

Bleyer, A J

Polyol pathway mediates high glucose-induced collagen synthesis in proximal tubule. [electronic resource] - Kidney international Mar 1994 - 659-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0085-2538

10.1038/ki.1994.88 doi


Aldehyde Reductase--antagonists & inhibitors
Animals
Cell Line
Cells, Cultured
Chloramphenicol O-Acetyltransferase--metabolism
Collagen--biosynthesis
Gene Expression
Genes, Reporter
Glucose--pharmacology
Imidazoles--pharmacology
Imidazolidines
Kidney Tubules, Proximal--drug effects
Mice
RNA, Messenger--metabolism
Sorbitol--metabolism
Transcriptional Activation
Transfection