Regulation of low density lipoprotein receptor and 3-hydroxy-3-methyl-glutaryl-CoA reductase activities are differentially affected in Niemann-Pick type C and type D fibroblasts.
Sidhu, H S
Regulation of low density lipoprotein receptor and 3-hydroxy-3-methyl-glutaryl-CoA reductase activities are differentially affected in Niemann-Pick type C and type D fibroblasts. [electronic resource] - Biochemistry and cell biology = Biochimie et biologie cellulaire - 467-74 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0829-8211
10.1139/o93-069 doi
Blood
Blotting, Northern
Cell Line
Cholesterol--metabolism
Cholesterol Esters--metabolism
Esterification
Fibroblasts--metabolism
Humans
Hydroxymethylglutaryl CoA Reductases--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Kinetics
Lipoproteins, LDL--metabolism
Lovastatin--pharmacology
Niemann-Pick Diseases--metabolism
RNA, Messenger--metabolism
Receptors, LDL--genetics
Sterol O-Acyltransferase--antagonists & inhibitors
Regulation of low density lipoprotein receptor and 3-hydroxy-3-methyl-glutaryl-CoA reductase activities are differentially affected in Niemann-Pick type C and type D fibroblasts. [electronic resource] - Biochemistry and cell biology = Biochimie et biologie cellulaire - 467-74 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0829-8211
10.1139/o93-069 doi
Blood
Blotting, Northern
Cell Line
Cholesterol--metabolism
Cholesterol Esters--metabolism
Esterification
Fibroblasts--metabolism
Humans
Hydroxymethylglutaryl CoA Reductases--metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Kinetics
Lipoproteins, LDL--metabolism
Lovastatin--pharmacology
Niemann-Pick Diseases--metabolism
RNA, Messenger--metabolism
Receptors, LDL--genetics
Sterol O-Acyltransferase--antagonists & inhibitors