Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum.

Gamage, S A

Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum. [electronic resource] - Journal of medicinal chemistry May 1994 - 1486-94 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm00036a014 doi


Aminoacridines--chemical synthesis
Animals
Antimalarials--chemical synthesis
Cell Division--drug effects
Cells, Cultured
Drug Resistance
Erythrocytes--parasitology
Humans
Plasmodium falciparum--drug effects
Structure-Activity Relationship
Topoisomerase II Inhibitors
Tumor Cells, Cultured