Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA.
Laptev, A V
Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA. [electronic resource] - Biochemistry Sep 1994 - 11033-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi00202a024 doi
3T3 Cells
Animals
Base Sequence
Binding Sites
Collagen--genetics
DNA Primers
Gene Expression Regulation--drug effects
Humans
Mice
Molecular Sequence Data
Nucleic Acid Conformation
Oligonucleotides, Antisense--pharmacology
RNA, Messenger--chemistry
Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA. [electronic resource] - Biochemistry Sep 1994 - 11033-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi00202a024 doi
3T3 Cells
Animals
Base Sequence
Binding Sites
Collagen--genetics
DNA Primers
Gene Expression Regulation--drug effects
Humans
Mice
Molecular Sequence Data
Nucleic Acid Conformation
Oligonucleotides, Antisense--pharmacology
RNA, Messenger--chemistry