Interaction of a series of nitriles with the alcohol-inducible isoform of P450: computer analysis of structure-activity relationships.

Lewis, D F

Interaction of a series of nitriles with the alcohol-inducible isoform of P450: computer analysis of structure-activity relationships. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems May 1994 - 401-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0049-8254

10.3109/00498259409043243 doi


Biotransformation
Computer Simulation
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Induction--drug effects
Ethanol--pharmacology
Isoenzymes--biosynthesis
Models, Biological
Nitriles--metabolism
Oxidation-Reduction
Oxidoreductases, N-Demethylating--biosynthesis
Predictive Value of Tests
Structure-Activity Relationship