Use of a biophysical-kinetic model to understand the roles of protein binding and membrane partitioning on passive diffusion of highly lipophilic molecules across cellular barriers.

Raub, T J

Use of a biophysical-kinetic model to understand the roles of protein binding and membrane partitioning on passive diffusion of highly lipophilic molecules across cellular barriers. [electronic resource] - Journal of drug targeting 1993 - 269-86 p. digital

Publication Type: Journal Article

1061-186X

10.3109/10611869308996085 doi


Animals
Autoradiography
Brain--metabolism
Cell Membrane--metabolism
Cells--metabolism
Chemical Phenomena
Chemistry, Physical
Chromans--chemistry
Diffusion
Dogs
Free Radical Scavengers
Indicators and Reagents
Kinetics
Membranes, Artificial
Models, Biological
Piperazines--chemistry
Pregnatrienes--chemistry
Protein Binding
Rats
Rats, Sprague-Dawley