Characterization of the inotropic and arrhythmogenic action of the sodium channel activator BDF 9148: a comparison to its S-enantiomer BDF 9196, to its congener DPI 201-106, to norepinephrine, and to ouabain.

Baumgart, D

Characterization of the inotropic and arrhythmogenic action of the sodium channel activator BDF 9148: a comparison to its S-enantiomer BDF 9196, to its congener DPI 201-106, to norepinephrine, and to ouabain. [electronic resource] - Basic research in cardiology - 61-79 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0300-8428

10.1007/BF00788678 doi


Analysis of Variance
Animals
Aorta--physiology
Azetidines--pharmacology
Blood Pressure--drug effects
Cardiotonic Agents--pharmacology
Dogs
Electric Stimulation
Electrocardiography--drug effects
Heart Rate--drug effects
Hemodynamics--drug effects
Isomerism
Myocardial Contraction--drug effects
Norepinephrine--pharmacology
Ouabain--pharmacology
Piperazines--pharmacology
Regional Blood Flow--drug effects
Sodium Channels--drug effects
Vascular Resistance--drug effects
Ventricular Function, Left--drug effects