(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid and related compounds: high affinity leukotriene B4 receptor antagonists.

Daines, R A

(E)-3-[[[[6-(2-carboxyethenyl)-5-[[8-(4- methoxyphenyl)octyl]oxy]-2-pyridinyl]-methyl]thio]methyl]benzoic acid and related compounds: high affinity leukotriene B4 receptor antagonists. [electronic resource] - Journal of medicinal chemistry Sep 1994 - 3327-36 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm00046a017 doi


Benzoates--chemistry
Binding, Competitive
Calcium--blood
Crystallography, X-Ray
Cytoplasmic Granules--drug effects
Humans
Leukotriene B4--metabolism
Molecular Structure
Neutrophils--drug effects
Pyridines--chemistry
Receptors, Leukotriene B4--antagonists & inhibitors
Structure-Activity Relationship