Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor.

Nykjaer, A

Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor. [electronic resource] - The Journal of biological chemistry Oct 1994 - 25668-76 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258


3T3 Cells
Animals
Antibodies, Monoclonal
Endocytosis--physiology
Enzyme Precursors--metabolism
Humans
Immunoglobulin Fab Fragments
Low Density Lipoprotein Receptor-Related Protein-1
Mice
Models, Biological
Plasminogen Activator Inhibitor 1--immunology
Plasminogen Activators--metabolism
Protein Binding
Receptors, Cell Surface--metabolism
Receptors, Immunologic--metabolism
Receptors, LDL--metabolism
Receptors, Urokinase Plasminogen Activator
Recombinant Proteins--immunology
Structure-Activity Relationship
Urokinase-Type Plasminogen Activator--immunology