Cyclic benzamides as mixed dopamine D2/serotonin 5-HT2 receptor antagonists: potential atypical antipsychotic agents.

Norman, M H

Cyclic benzamides as mixed dopamine D2/serotonin 5-HT2 receptor antagonists: potential atypical antipsychotic agents. [electronic resource] - Journal of medicinal chemistry Aug 1994 - 2552-63 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm00042a008 doi


Animals
Antipsychotic Agents--chemical synthesis
Apomorphine--pharmacology
Behavior, Animal--drug effects
Binding, Competitive
Catalepsy--chemically induced
Corpus Striatum--metabolism
Cyclization
Dopamine D2 Receptor Antagonists
Frontal Lobe--metabolism
Hippocampus--metabolism
Indoles--chemical synthesis
Isoindoles
Male
Mice
Molecular Structure
Motor Activity--drug effects
Phthalazines--chemical synthesis
Radioligand Assay
Rats
Rats, Sprague-Dawley
Receptors, Dopamine D2--metabolism
Receptors, Serotonin--metabolism
Serotonin Antagonists
Structure-Activity Relationship
Thiazoles--chemical synthesis