Modification by brefeldin A, bafilomycin A1 and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD) of cellular accumulation and intracellular distribution of anthracyclines in the non-P-glycoprotein-mediated multidrug-resistant cell line COR-L23/R.

Rhodes, T

Modification by brefeldin A, bafilomycin A1 and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD) of cellular accumulation and intracellular distribution of anthracyclines in the non-P-glycoprotein-mediated multidrug-resistant cell line COR-L23/R. [electronic resource] - British journal of cancer Jul 1994 - 60-6 p. digital

Publication Type: Journal Article

0007-0920

10.1038/bjc.1994.250 doi


4-Chloro-7-nitrobenzofurazan--pharmacology
ATP Binding Cassette Transporter, Subfamily B, Member 1
Anti-Bacterial Agents--pharmacology
Antibiotics, Antineoplastic--pharmacokinetics
Brefeldin A
Carcinoma, Non-Small-Cell Lung--metabolism
Carrier Proteins
Cell Nucleus--metabolism
Cyclopentanes--pharmacology
Cytoplasm--metabolism
Daunorubicin--pharmacokinetics
Doxorubicin--pharmacokinetics
Drug Interactions
Drug Resistance--physiology
Drug Screening Assays, Antitumor
Golgi Apparatus--drug effects
Humans
Lung Neoplasms--metabolism
Macrolides
Membrane Glycoproteins
Protein Synthesis Inhibitors--pharmacology
Proton-Translocating ATPases--antagonists & inhibitors
Tetrazolium Salts
Thiazoles
Tumor Cells, Cultured--drug effects