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Are we doing too many animal biodisposition investigations before phase I studies in man? A re-evaluation of the timing and extent of ADME studies.

Campbell, D B

Are we doing too many animal biodisposition investigations before phase I studies in man? A re-evaluation of the timing and extent of ADME studies. [electronic resource] - European journal of drug metabolism and pharmacokinetics - 283-93 p. digital

Publication Type: Journal Article

ISSN: 0378-7966

Standard No.: 10.1007/BF03188932 doi

Subjects--Topical Terms:
Animals
Clinical Trials, Phase I as Topic
Cytochrome P-450 Enzyme System--physiology
Humans
Pharmacokinetics
Protein Binding
Time Factors

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