Purification and characterization of a rat liver enzyme that hydrolyzes valaciclovir, the L-valyl ester prodrug of acyclovir.

Burnette, T C

Purification and characterization of a rat liver enzyme that hydrolyzes valaciclovir, the L-valyl ester prodrug of acyclovir. [electronic resource] - The Journal of biological chemistry Jun 1995 - 15827-31 p. digital

Publication Type: Journal Article

0021-9258

10.1074/jbc.270.26.15827 doi


Acyclovir--analogs & derivatives
Amino Acid Sequence
Animals
Antiviral Agents--metabolism
Biotransformation
Hydrolases--chemistry
Liver--enzymology
Male
Molecular Sequence Data
Prodrugs--metabolism
Rats
Valacyclovir
Valine--analogs & derivatives