Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study.

Groutas, W C

Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study. [electronic resource] - Bioorganic & medicinal chemistry Feb 1995 - 125-8 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0968-0896

10.1016/0968-0896(95)00006-3 doi


Cathepsin G
Cathepsins--antagonists & inhibitors
Humans
Isoxazoles--chemical synthesis
Kinetics
Leukocyte Elastase
Magnetic Resonance Spectroscopy
Molecular Structure
Myeloblastin
Pancreatic Elastase--antagonists & inhibitors
Protease Inhibitors--chemical synthesis
Serine Endopeptidases--drug effects
Structure-Activity Relationship