Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase.

Glass, D B

Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase. [electronic resource] - Protein science : a publication of the Protein Society Mar 1995 - 405-15 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0961-8368

10.1002/pro.5560040307 doi


Amino Acid Sequence
Carrier Proteins--chemistry
Circular Dichroism
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
Dose-Response Relationship, Drug
Drug Design
Intracellular Signaling Peptides and Proteins
Models, Molecular
Molecular Sequence Data
Peptide Fragments--chemistry
Protein Binding
Protein Structure, Secondary
Solutions
Spectroscopy, Fourier Transform Infrared
Structure-Activity Relationship
Water--chemistry